what is Addison’s disease? Give detail about aldosterone?
what is Addison’s disease? Give detail about aldosterone?

A female patient presented to her physician appeared thin, with sunken eyes. She told her physician that she has lost 20 pounds, she faces extreme fatigue and she has not had a menstrual period in the last three months.
Recorded blood pressure was very low (70/35) and pulse rate increased 120 beats/min. Her skin was deeply pigmented especially at nipples and in the creases of the hands. Labs tests showed:
- Decreased Na ions, increased potassium ions, decreased osmolality, decreased fasting glucose, decreased cortisol and aldosterone, and increased ACTH.
Based on the physical appearance and lab tests, what is your diagnosis, and what are the clinical features of the disease? Give details about biosynthesis of aldosterone, its mechanism of action, functions of aldosterone, and regulation of aldosterone?
what is Addison’s disease? Give detail about aldosterone?
what is Addison’s disease? Give detail about aldosterone?
A female patient presented to her physician appeared thin, with sunken eyes. She told her physician that she has lost 20 pounds, she faces extreme fatigue and she has not had a menstrual period in the last three months.
Recorded blood pressure was very low (70/35) and pulse rate increased 120 beats/min. Her skin was deeply pigmented especially at nipples and in the creases of the hands. Labs tests showed:
Based on the physical appearance and lab tests, what is your diagnosis, and what are the clinical features of the disease? Give details about biosynthesis of aldosterone, its mechanism of action, functions of aldosterone, and regulation of aldosterone?